Successful cultivation in vitro Hepatitis C virus
According to the latest issue of “American pathology journals” (The American Journal of Pathology), a paper that scientists have broken through the bottleneck of patients separated from the liver cells (hepatocytes), together with the patient’s serum (Serum) , successfully cultured in vitro Hepatitis C virus (Hepatitis C Virus).
Clinical lead to liver inflammation, cirrhosis, liver cancer and liver transplant led to the needs of the main reasons is that hepatitis C virus infection, according to international statistics related health units, the global population of about 170 million, infection this is a threat of disease, hepatitis C virus but the most serious problem is that the virus no way in vitro, resulting in drug research and development progress has been rather slow.
Kingston University School of Medicine, St. Dr. Nelson Fausto of the research team, the use of human fetal liver cells (hepatocyte), the development of the hepatitis C virus in vitro system, confirmed hepatitis C virus can indeed in Petri dishes, a copy survival 2, the researchers then infected with different strains of hepatitis C virus in the serum of patients, the virus added to the medium, confirming that the new generation of virus particles, not only in the replication cycle of infection of the liver with a cycle, and even the freshmen the virus particles, but also healthy liver cells infected with the capacity.
Now researchers in-depth analysis of this newly developed virus cultivation systems, and different strains of hepatitis C virus between the relationship, and we hope to really control this special virus activities of the secret to accelerate drug development.
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