Purpura and the EB virus

Immune thrombocytopenia purpura is a common children’s blood diseases, Kaohsiung Chang Gung Children’s Hospital pediatric oncology blood found on the EB virus, can globulin or high-dose steroid treatment, but if non-EB virus, must be other ways to Treatment.

Immune thrombocytopenia purpura is in the blood of a number of spontaneous anti-platelet antibodies, and attached to the platelets, the lead was swallowed cell damage, a serious decrease the number of platelets, the normal platelet count in the 150,000 to 400,000, immunization Thrombocytopenia purpura patients only a few thousand to one, 20,000.

Immune thrombocytopenia purpura occur in two to five-year-old child, the majority of cases the onset of the first three, four weeks or at the same time, a respiratory tract infection symptoms, it is often misdiagnosed as common cold, is unknown, but the infection was medical That the sector is an important pathogenic factor.

Kaohsiung Chang Gung Children’s Hospital pediatric oncology director of the blood on the 9th Chih-Cheng Hsiao said that child care skin blood, up or bruise, epistaxis bleeding or mucosal immune thrombocytopenia purpura common illnesses, or even 1% of intracranial hemorrhage Leading to death.

Hospital pediatric blood cancer diagnosis and treatment of the past decade 108 immune thrombocytopenia purpura young children, aged from one month to 16 years old, the average age of 4.5 years, testing has confirmed that 35 people are due to EB virus Trigger, and the other 73 were non-EB virus.

Including two 10-year-old girls intracranial hemorrhage due to the death rather than rule, they are not EB virus, because the globulin, the slow response to steroids, the platelet count increased slowly, leading to death.

Chih-Cheng Hsiao said that 90 percent of children in Taiwan in the 20-year-old former EB virus infection, far more than abroad, is the main reason parents Juesui Food and feeding young children.

Most people infected with the virus after the EB will recover, but the existence of the human body the virus, spread by Koumo, in addition to trigger immune thrombocytopenia purpura, a more serious cause infectious mononucleosis more of the ball (commonly known as the kissing disease), hemolytic Anemia, renewable bad anemia, the virus relevance of hemophagocytic syndrome, ruptured spleen and Alice in Wonderland syndrome, even with lymphoma, nasopharyngeal cancer-related.

He said, EB virus and non-EB virus induced immune thrombocytopenia purpura symptoms similar, but different treatment modalities, to determine if the EB virus, immunoglobulin or high-dose steroids is the best therapy.

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