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“Capsule endoscopy” known as “intelligent capsule Gastrointestinal Endoscopy System,” also known as the “Medical wireless endoscope.” Its working principle is: Oral subjects through a built-in camera and signal transmission devices Intelligent capsule, through the gastrointestinal peristalsis in the upper gastrointestinal movement and photographed image, the image in vitro doctors use recording devices and imaging workstations, understanding subjects of the entire digestive tract, thereby making the diagnosis of their condition . A convenient capsule endoscopy examination, no trauma, no wires, no pain, no cross-infection does not affect the normal working of the advantages of expanding the gastrointestinal examination vision to overcome the traditional insertion of the endoscope with the tolerance of difference, not for the frail and elderly in critical condition and defects, as gastrointestinal diseases, particularly intestinal disease diagnostic method of choice by the medical profession as the 21st century revolution and the development of endoscopic direction. A world history of the development of capsule endoscopy
Human pry into their own in the slightest interest in the mysteries of no less than the external environment of curiosity, the history of endoscopy and Western medical history almost as long.
The title of the Father of Medicine Hippocrates described in Greece had a “advice of the rectum.” Since 1806 German Tamara created to light candles for the bladder-rectum, endoscopy with the advancement of technology and human development: from the hard-endoscope, fiber endoscopy, ultrasound and electronic endoscope, the doctor has been able to use these devices more convenient, more clear closely watching the human body and the internal organs.
Over the past 20 years, with the current scientific advances in related technologies, gastroendoscope rapid development of technology, particularly endoscopic interventional treatment technology is more rapid diagnosis and treatment of digestive diseases has become an indispensable technology, to a certain extent, certain digestive diseases replace traditional surgery treatment.
In 1981, the Israeli Defense Ministry mechanical engineer curve listen to a physician chatted endoscopic examination process, he reminds himself familiar with the smart missiles remote camera installations, and the resulting development of a wireless endoscope originally envisioned. Since then, the curve led by the Israeli experts began vigorously wireless endoscope research work, and in the 1990s was the first technology patents. In 2001, Israel’s Given Imaging companies curve patented technologies produced the world’s first pill called a capsule endoscopes, and the first to enter clinical use of this product in the world has aroused tremendous repercussions.
Capsule Endoscopy Endoscopy opened the birth of a new medical technology field, and with gastroscopy and colonoscopy has a good complementary, and is subject to digest history of the development of an important milestone.
After this, many countries in the world have begun the study of micro-capsules clinics digestive system research and development work, and that the diagnosis of gastrointestinal diseases and treatment toward painless, noninvasive direction. In recent years, various intelligent capsule products have appeared, and in the function of their own talent. For example, in the digestive tract can be completed within the targeted delivery “remote control release capsule”; Also in the digestive tract within the sampling capsule; The United States Diagnostics develops products “smart pill” (Smart pill) is dedicated to detecting gastrointestinal internal pressure, pH and other indicators, which For more information, “gastroesophageal reflux disease” and other gastrointestinal motility of disease diagnosis is important; South Korea’s Ministry of Science and Technology Development Organization, “capsule Robot” is in complete control in vitro drug release, image acquisition, biopsy and treatment of a variety of functions, but such a versatile head capsule the former is still in the prototype stage.
2, domestic capsule endoscopy breakthroughs and technical characteristics
In 2001, Chongqing Jinshan technology group, “capsule endoscopy” independent research and development, and in October 2002 the Ministry of Science and Technology international cooperation projects, but also was included in the “863 Program” advanced manufacturing and automation to the field of MEMS major special support. After more than three years of painstaking research, Jinshan Chongqing Technology Group finally completed in early 2004 capsule endoscopy key technology development, came up with a prototype; After a series of animal tests, in June 2004 of the first-generation products stereotypes.
Chongqing Jinshan Technology Group capsule endoscopy was named “OMOM”, in March 2004 from the Chinese SFDA approval, the granting of clinical application. It was the first one, of course, is the world’s second capsule endoscopy for clinical.
OMOM capsule endoscopy is set image processing, information communications, opto-electronics, biomedical technology and multidisciplinary integration of the typical micro-electromechanical systems (MEMS) technology, the smart capsule, image and video recording devices to workstations (computer and image analysis software) is composed of three parts. Doctors can help patients with digestive tract disease diagnosis, diagnosis and treatment of digestive diseases have a very wide range of applications.
OMOM capsule endoscopy is the working principle: with the same medication as intelligent water swallowed capsules, it is with gastrointestinal muscle movement along the rhythm of gastric duodenal → → → jejunum and ileum → colon rectal running in the direction, right through the cavity of continuous video, and digital signal transmission plan as for the patient in vitro with the image recorder to record storage, work time is six to eight hours in the smart capsule obtain eight to 72 hours after will be excreted with faeces. Doctors imaging workstation images recorded by the instrument can record images of the patients throughout the digestive tract, thereby making the diagnosis of disease.
OMOM capsule endoscopy operation is very simple, the entire inspection only obtain capsule, and recorded three intervals of the process. Doctors only in intervals of the process, to take pictures through the right conditions can be accurately judged. OMOM capsule endoscopy in the early research and development, adopted a foreign patents totally different design and technology, and validate the technical feasibility of a number of breakthroughs in key technologies, including: low-power image acquisition and processing system design, close-King aspherical lens design, duplex Multi-channel wireless transmission design and packaging technology and structural strength, consistency and reliability.
OMOM capsule endoscopy is the main innovation point two aspects: First, the wireless transceiver controllable manner. Only foreign product launch function, and image recording devices only passive receivers, the capsule can not be achieved in vitro control; OMOM capsule endoscopy capsule and the Intelligent Image Recorder wireless duplex multichannel approach to communications, with the reception and control functions. Two imports capsule endoscopy is only after the completion of filming in the delivery of workstations out images. While domestic OMOM capsule endoscopy true color image of the real-time monitoring, intelligent doctors capsules facilitate detection process completed work on the Smart Capsule state control, but also established an open port is conducive to the future of the capsule in vitro control.
3, homemade capsule endoscopy in clinical application
Israel GI’s M2A capsule endoscopy since 2002 after entering China, has more than 30 hospitals to introduce the equipment, however, because some features of limitations, particularly high price (in the early patients as a check on the cost of 8,000 yuan to 10,000 yuan around), , the use of quantitative be greatly affected.
Compared with imported capsule endoscopy, capsule endoscopy in OMOM domestic prices substantially lower, a check charges around 3,000 yuan, while technically has its own unique advantages, since OMOM capsule endoscopy, it has its low price, high-tech and quickly occupied the market. Currently in Beijing Friendship Hospital, Beijing Military General Hospital, Shanghai Changhai Hospital, Huaxi Hospital in Chengdu, Guangzhou Nanfang Hospital Xinqiao Hospital in Chongqing and more than 40 major hospitals in clinical use.
Capsule endoscopy in clinical application value has been a troubled hospitals and manufacturers of a problem. They are all from different angles to the orientation of value. The first time, Israel’s position in the whole digestive tract pill checks, but, because of a stomach cavity, and can not be the right time for the period of control, so too random, not as a screening option stomach with endoscopy technology has been very mature, so the difference pill of choice positioning only clear pill for the small bowel examination. Because of the small intestine for 5-7 meters long been known as clinical examination of blind spots.
Domestic OMOM capsule endoscopy in the clinical value of the location, manufacturers take a completely different line of thought. They will OMOM value of capsule endoscopy, located in three aspects: First, check comfortable means to meet the tolerance of poor people and the investigation of high-end crowd investigations; Two means of diagnosis and treatment is integrated with other means of gastrointestinal examination with a view to improve the diagnostic accuracy; The breakthrough means three small intestine, the traditional method can not achieve the true color image of small intestine checks.
The birth of capsule endoscopy, in addition to the small intestine blind spot outside a major breakthrough to make early diagnosis of gastrointestinal disease to fruition. There is a Chinese saying, called “prevention.” However, in clinical To achieve this, but also the need for advanced, safe, comfortable with the medical equipment. While many of the current treatment and screening devices failed to do so painless non-invasive, patients have a psychological fear and exclusion, can lead to many diseases found in the early, so “is a late discovery.” OMOM capsule endoscopy is a new, safe and comfortable means of gastrointestinal examination, it could remove the patient’s fear of the examination, the patients accept, thereby OMOM capsule endoscopy with the early diagnosis of gastrointestinal diseases important value.
OMOM capsule endoscopy Clinical application has shown that, in addition to some patients because of the pain and accept inspections, have more than half of the subjects are medical in nature. That capsule endoscopy examination in the area also has a broader application of space. With the improvement of the quality of life of people, the pursuit of health has become a necessity. If OMOM capsule endoscopy to vigorously promote the use of physical examination can be expected nationals advanced gastrointestinal disease incidence would be greatly reduced.
4, capsule endoscopy future and the need to resolve the issue
As technology continues to evolve, the capsule endoscopy intelligence will continue to increase its function will be further strengthened, in clinical applications will be even more magical.
The future will be the development of capsule endoscopy how? China gastroendoscope director of the Institute of Professor Zhang Qi Prospect capsule endoscopy in the future, its image has been likened to “hand with legs” Intelligent capsule. “Foot” means the capsule can move around freely within the human gut, which means doctors can control the patient through in vitro capsule and running posture to better check; “Hand”, it means that capsule endoscopy in the body to spot drug release, and even some simple surgical treatment to help doctors intestinal resection of the tumors or polyps. To achieve these functions, but also need to address the following questions:
A wireless electricity, solve the energy problem
But in the future capsule “in hand with legs” ideal state, how to solve the energy problems capsule itself, it has become particularly pronounced. Capsule to the future control of in vitro and in vivo treatment, electricity will cost more, the conventional battery, it is already very difficult to maintain. So, how can we guarantee that capsule in the body has sufficient energy to complete tasks, as capsule endoscopy in the future the most important condition for success.
Currently, Jinshan technology technical staff who are trying to abolish batteries, to develop MEMS (micro-electromechanical systems)? ? Permit the use of capsules in the process, to have continuous current to the directives issued by the external completed.
2, precision positioning, ensure effectiveness
At present, capsule endoscopy in the past can not check for a period of five to seven meters from the small intestine to provide a viable inspection program, but along the capsule failed to capture images for accurate positioning. In other words, patients with capsule endoscopy and found lesions, which puzzled doctors for changing the location of lesions, doctors only images of the cases and time capsule to judge his position is far from enough, so the capsule endoscopy can be a quasi-positioning become imperative, the only way , a surgeon can give the precise location of the operation, rather than the previous “discredit exploration.”
3, increase the controllability of the capsule, achieving biopsy, pesticide control and direction
Capsule endoscopy painless, non-invasive, non-wire comfort gastrointestinal endoscopic examination concept is the development of a future direction. Of course, a perfect capsule endoscopy function also needs a very long time, and now the capsule endoscopy beyond its limitations also led to replace the traditional plug-in gastrointestinal endoscopy. Although the domestic OMOM capsule to a certain extent, control the frequency and precision shooting, movement and gesture, the capsule control capsule endoscopy is the real direction of development. Achieving biopsy, pesticide control and direction of development of a capsule endoscopy on the road to overcome the difficulties, so that capsule endoscopy replace traditional gastroendoscope only become a possibility.