Detection of plasma know leukemia prognosis
To a determination of plasma levels of sFas assessment of acute leukemia activity and prognosis of subjects, in Guangxi recently completed Nanxi Hill Hospital. Dr. Liu Taowen the hospital through the Group of 100 patients observed the test, suggesting that acute leukemia is a high level of plasma sFas condition Nankong Zhi, the effect of chemotherapy and the prognosis is poor.
Liu Tao, and so from the perspective of molecular biology to actively explore plasma soluble Fas receptor on the way to interfere with apoptosis, using ELISA determination of plasma levels of sFas. Its performance indicators, in 54 acute myeloid leukemia and 46 patients with acute lymphoblastic leukemia in the two groups, complete remission and relapse refractory plasma levels of sFas were significantly different (P <0.01); between the two groups of complete remission And the refractory recurrence, the difference was not obvious (P> 0.05); complete remission with normal controls, plasma sFas also no significant difference, also found that detection of increased levels of sFas are bad effects of chemotherapy.
Molecular sFas apoptosis in leukemia patients in the determination of blood for clinical monitoring the evolution of acute leukemia, and select the vesting of options to provide a meaningful technical indicators.
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