Ectopic pregnancy pathological cognitive
1. Tubal pregnancy and the changes in the outcome of tubal lumen small, thin wall and the absence of mucosal tissue, far less muscular uterine muscle wall thickness and tenacity, not a good pregnancy when the decidua, are unable to meet the growth and development of embryos, When tubal pregnancy develops to a certain period, will result in the following:
(1) tubal pregnancy abortion: ampulla was particularly prevalent in the fallopian tube pregnancy, the incidence of pregnancy in more than 8-12 weeks. Fertilized eggs planted in the Ovductal fold as a result of tubal pregnancy wall decidual incomplete formation, development to the blastocyst often lumen prominent, and finally broke through capsule hemorrhage, with the wall of separation blastocyst, if the entire capsule embryo dissection into the fallopian tube lumen and reverse peristalsis-the umbrella from the abdominal cavity, a tubal complete abortion, hemorrhage generally small. If the blastocyst stripping incomplete pregnancy from the abdominal cavity of the product, some still attached to the fallopian tube wall, a tubal incomplete abortion, tubal trophoblast cells continue to erode the wall, leading to repeated bleeding, hematoma or tubal fallopian tube formed around hematoma. Because tubal muscle wall thin, poor contractile force, it is not easy to stop bleeding, the blood outflow, the accumulation of uterine lacunae in the formation of rectal pelvic hematoma, or even in large quantities into the abdominal cavity.
(2) ruptured tubal pregnancy: Gap was particularly prevalent in the tubal pregnancy, the incidence of pregnancy and more in about six weeks. Ovductal fertilized egg implantation in the plica, when blastocyst growth villosity direction to the erosion of muscle wall and serosa, finally pierced serosa, a ruptured tubal pregnancy. Tubal muscle vascular rich ruptured tubal pregnancy-induced hemorrhage intense than tubal pregnancy abortion, in the short term can be so massive intraperitoneal hemorrhage patients in a shock, and also repeated bleeding, pelvic and abdominal hematoma formation. Of interstitial pregnancy Although rare, but serious consequences, the outcome of almost all of tubal pregnancy ruptured.
Department of interstitial-uterine horn into the muscle wall of the cavity surrounding myometrium thick, it can be maintained to four months of pregnancy would only occur about rupture. The rich blood supply here, like rupture of uterine rupture, very serious symptoms often occur in a short period of time a large number of intra-abdominal hemorrhage. Ruptured tubal pregnancy or abortion, and sometimes stop internal bleeding in a stable condition, long time, embryonic death or absorption. But long-term repeated bleeding hematoma formed by the pelvic not dissipated, and stiffen hematoma of the machine and surrounding tissue adhesion, clinically known as Old ectopic pregnancy.
(3) secondary abdominal pregnancy: whether abortion or ruptured tubal pregnancy, the general blastocysts from the fallopian tube or abdominal cavity from the broad ligament, the majority of deaths, not growth, but occasionally there are those who survived, if the survival of embryos villi organization remains in situ or exclusivity attached to the abdominal cavity after replanting to receive nutrition, can be formed to continue the growth and development of secondary abdominal pregnancy. If the broad ligament rupture in the mouth, can be developed for the broad ligament pregnancy.
2. Tubal pregnancy in the uterus and normal pregnancy, trophoblast cells of the HCG luteal growth, the increase in steroid hormone secretion. Therefore, the cessation of menstrual cramps, increased soft uterine endometrium in decidual response. If embryonic death, trophoblastic vitality disappeared since decidual Palace wall dissection in vaginal bleeding. Sometimes decidual integrity can be separated, with vaginal bleeding from the decidua of the triangle; sometimes showed debris from. Villi seen from the organization, histological examination with trophoblast cells. Morphological changes of endometrial was diversity, with the exception of a decidual endometrial changes, if the embryo has been long dead, endometrial hyperplasia can be a period of change, and sometimes that Arias-Stella (AS) reaction examination see endometrial glands Epithelial cell proliferation, increased endometrial glandular cells, cell borders unclear, glandular cells arranged Mission suddenly people gland cavity, cell polarity disappeared, mast cells, deeply stained, cytoplasmic vacuolation. This endometrial hyperplasia and secretion response to steroid hormones may be caused by excessive stimulation, although the diagnosis of a certain value, but not unique tubal pregnancy. In addition, after the death of embryos, some of the villi in-depth muscle still alive, luteal slow degradation, secretion was still endometrial response.